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Series GSE99904 Query DataSets for GSE99904
Status Public on Jun 03, 2018
Title Glucose competition between immune cells and microbial pathogens controls infections
Organisms Candida albicans; Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary To understand the dynamic physiological changes in host and pathogen that occur during infection, some of which might be driving the ability of C. albicans to trigger macrophage cell death, we performed dual RNA-seq of C. albicans-infected bone marrow-derived mouse macrophages over a time course. We chose three time points corresponding to: (i) early events post-phagocytosis of C. albicans (approximately 1 h post infection), (ii) fungal escape following caspase 1-dependent pyroptosis (approximately 6 h post infection), and (iii) the transition to the rapid Phase II death (approximately 9 h post-infection).
Overall design Analysis of dual RNA-seq in C. albicans
Contributor(s) Traven A, Harrrison PF, Beilharz TH
Citation(s) 29719235
Submission date Jun 12, 2017
Last update date May 15, 2019
Contact name Traude Beilharz
Organization name Monash University
Department Biomedicine Discovery Institute
Lab RNA Systems Biology Laboratory
Street address Wellington Rd
City Clayton
State/province VIC
ZIP/Postal code 3800
Country Australia
Platforms (2)
GPL18480 Illumina HiSeq 1500 (Mus musculus)
GPL23573 Illumina HiSeq 1500 (Candida albicans)
Samples (18)
GSM2664012 Sample_E1_Ca1
GSM2664013 Sample_E1_Ca6
GSM2664014 Sample_E1_Ca9
BioProject PRJNA390053
SRA SRP108976

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE99904_calbicans_count.csv.gz 159.2 Kb (ftp)(http) CSV
GSE99904_calbicans_tail.csv.gz 428.2 Kb (ftp)(http) CSV
GSE99904_calbicans_tail_count.csv.gz 152.3 Kb (ftp)(http) CSV
GSE99904_mouse_count.csv.gz 521.8 Kb (ftp)(http) CSV
GSE99904_mouse_tail.csv.gz 999.3 Kb (ftp)(http) CSV
GSE99904_mouse_tail_count.csv.gz 475.3 Kb (ftp)(http) CSV
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Raw data are available in SRA
Processed data are available on Series record

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