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Series GSE99157 Query DataSets for GSE99157
Status Public on May 21, 2020
Title the lncRNA expression profiles in fetal liver, adult liver and liver cancer tissues from mice
Organism Mus musculus
Experiment type Non-coding RNA profiling by array
Summary A large number of oncofetal molecules were found through expression profiling of a total of lncRNAs(35923)+coding genes(24881) from 17.5-day-old embryonic livers (three independent replicate samples named A1, A2, and A3), 2-month-old adult male mouse livers (three independent replicate samples named B1, B2, and B3) and one-year-old male mouse liver cancer tissues (three independent replicate samples named C1, C2, and C3) using a microarray analysis.
 
Overall design To identify some oncofetal transcripts that potentially affect the occurrence and development of HCC, we established a DEN-induced mouse liver cancer model to obtain experimental samples considering the individual differences in human HCC samples, which are referred to as liver cancer in the following narrative. The liver cancer tissues were subjected to haematoxylin-eosin staining (HE staining) and verified according to their cell morphology under a microscope. Then, we analyzed the expression profiles of lncRNAs and protein-coding RNAs in 17.5-day-old embryonic livers (three independent replicate samples named A1, A2, and A3), 2-month-old adult male mouse livers (three independent replicate samples named B1, B2, and B3) and one-year-old male mouse liver cancer tissues (three independent replicate samples named C1, C2, and C3) using a microarray analysis.
 
Contributor(s) Liu Y, Wang F
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Submission date May 22, 2017
Last update date Jul 25, 2021
Contact name Yan Liu
E-mail(s) 15026971620@163.com
Phone 15026971620
Organization name Second Military Medical University, Shanghai 200433, China
Department The Department of Medical Genetics
Lab The Department of Medical Genetics
Street address 800 Xiangyin Road, Shanghai 200433
City shanghai
State/province Shanghai
ZIP/Postal code 200433
Country China
 
Platforms (1)
GPL19286 Arraystar Mouse LncRNA microarray V3B (Agilent-055750 custom Probe Name version)
Samples (9)
GSM2634304 Fetal liver 1
GSM2634305 Fetal liver 2
GSM2634306 Fetal liver 3
Relations
BioProject PRJNA387445

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE99157_All_Comparison_LncRNAs.xls.gz 17.3 Mb (ftp)(http) XLS
GSE99157_All_Comparison_mRNAs.xls.gz 15.3 Mb (ftp)(http) XLS
GSE99157_Differentially_Expressed_LncRNAs_Pass_Volcano_Plot.xls.gz 6.2 Mb (ftp)(http) XLS
GSE99157_Differentially_Expressed_mRNAs_Pass_Volcano_Plot.xls.gz 6.9 Mb (ftp)(http) XLS
GSE99157_LncRNA_Expression_Profiling_Data.xls.gz 6.7 Mb (ftp)(http) XLS
GSE99157_RAW.tar 25.7 Mb (http)(custom) TAR (of TXT)
GSE99157_mRNA_Expression_Profiling_Data.xls.gz 6.3 Mb (ftp)(http) XLS
Processed data included within Sample table
Processed data are available on Series record

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