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Series GSE98522 Query DataSets for GSE98522
Status Public on May 04, 2017
Title Molecular Mediators of Cardiac Pathology in Cardiorenal Syndrome Type 4 [anti-miR-21]
Organism Rattus norvegicus
Experiment type Expression profiling by high throughput sequencing
Summary We report the changes in left ventricle mRNA abundance in response to miR-21-5p suppression in 5/6 nephrectomized rats.
Overall design Ten week old male Sprague Dawley rats were subjected to the excision model of 5/6 nephrectomy (5/6Nx) surgery. LNA-anti-scrambled or LNA-anti-miR-21-5p was delivered intravenously in 3 daily doses of 1 mg/kg at 1 and 4 weels post-surgery. Left ventricle tissue was collected for mRNA sequencing 7 weeks after surgery.
Contributor(s) Chuppa S, Liang M, Liu P, Liu Y, Casati MC, Cowley AW, Patullo L, Kriegel AJ
Citation(s) 28760335
Submission date May 03, 2017
Last update date Aug 01, 2019
Contact name Alison J. Kriegel
Phone (414)955-4835
Organization name Medical College of Wisconsin
Department Physiology
Lab Kriegel
Street address 8701 Watertown Plank Rd.
City Milwaukee
State/province WI
ZIP/Postal code 53226
Country USA
Platforms (1)
GPL14844 Illumina HiSeq 2000 (Rattus norvegicus)
Samples (4)
GSM2598207 SD_5/6Nx+anti-miR-21_RNASeq_rep1
GSM2598208 SD_5/6Nx+anti-miR-21_RNASeq_rep2
GSM2598209 SD_5/6Nx+anti-scr_RNASeq_rep1
This SubSeries is part of SuperSeries:
GSE97950 Molecular Mediators of Cardiac Pathology in Cardiorenal Syndrome Type 4
BioProject PRJNA385371
SRA SRP106489

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE98522_Supplemental_Table_4_anti-scr_vs._anti-miR-21_5-6Nx_Wk7.xlsx 2.6 Mb (ftp)(http) XLSX
GSE98522_Supplemental_Table_4_mapping_rate.xlsx 8.7 Kb (ftp)(http) XLSX
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Raw data are available in SRA
Processed data are available on Series record

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