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Series GSE97632 Query DataSets for GSE97632
Status Public on May 27, 2017
Title Methylation DNA mediated KLF4 binding activity in glioblastoma cells
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Methylation profiling by high throughput sequencing
Summary RNA-seq, ChIP seq and Whole genome bisulfite seq for KLF4-mCpG binding in GBM cells
 
Overall design We engineered two doxycycline-inducible U87 cell lines to express KLF4 wild type and mutant (R458A), and examined KLF4 binding, gene regulation and whole genome bisulfite seq in U87 cells
 
Contributor(s) Wan J, Su Y, Song Q, Tung B, Oyinlade O, Liu S, Ying M, Ming G, Song H, Qian J, Zhu H, Xia S
Citation(s) 28553926
Submission date Apr 11, 2017
Last update date May 15, 2019
Contact name Shuli Xia
E-mail(s) xia@kennedykriger.org
Phone 443-923-9498
Organization name Kennedy Krieger Institute
Street address 707 N Broadway
City Baltimore
State/province Maryland
ZIP/Postal code 21205
Country USA
 
Platforms (1)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
Samples (48)
GSM2573745 H3K27ac_ChIP-seq for R458A at 0hr
GSM2573746 H3K27ac_ChIP-seq for R458A at 48hr
GSM2573747 H3K27ac_ChIP-seq for WT at 0hr
Relations
BioProject PRJNA382497
SRA SRP103794

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE97632_FPKM_5Aza.xlsx 3.6 Mb (ftp)(http) XLSX
GSE97632_FPKM_r1.xlsx 3.3 Mb (ftp)(http) XLSX
GSE97632_FPKM_r2.xlsx 3.5 Mb (ftp)(http) XLSX
GSE97632_KLF4_ChIP-seq.xlsx 156.5 Kb (ftp)(http) XLSX
GSE97632_R458-H3K27AC-MACS2_peaks.xlsx 1.0 Mb (ftp)(http) XLSX
GSE97632_U87Dox_coverage2cytosine.txt.gz 272.8 Mb (ftp)(http) TXT
GSE97632_WT-H3K27AC-MACS2_peaks.xlsx 1.0 Mb (ftp)(http) XLSX
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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