GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE95272 Query DataSets for GSE95272
Status Public on Feb 24, 2017
Title Prominent oncogenic roles of EVI1 in breast carcinoma
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Overexpression of the Ecotropic viral integration site 1 (EVI1) gene typically associates with aggressive forms of leukemia. Aberrant EVI1 expression is also detected in breast carcinoma but its role in this tumor type is largely unknown. In order to analyze its effects in breast cancer, shRNA knockdown was performed on MDA-MB-231 cells and gene expression compared in EVI1 knockdown versus corresponding control shRNA treated cells.
Overall design MDA-MB-231 cells were lentivirally transduced with two independent shRNA construct targeting EVI1 expression and respectively two corresponding non-coding shRNA constructs as control. Cells were transduced and analyzed independently in three biological experiments.
Contributor(s) Wang H, Lengerke C
Citation(s) 28209621
Submission date Feb 23, 2017
Last update date Jan 09, 2018
Contact name Hui Wang
Organization name University Hospital Basel
Street address Hebelstr. 20
City Basel
ZIP/Postal code 4031
Country Switzerland
Platforms (1)
GPL17077 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
Samples (9)
GSM2501130 control shRNA 1
GSM2501131 control shRNA 2
GSM2501132 control shRNA 3
BioProject PRJNA376524

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE95272_RAW.tar 111.4 Mb (http)(custom) TAR (of TXT)
GSE95272_RS-292_MDAMB_2_alldata_normalized.txt.gz 9.3 Mb (ftp)(http) TXT
Processed data included within Sample table
Processed data are available on Series record

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap