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Series GSE95028 Query DataSets for GSE95028
Status Public on Mar 09, 2018
Title NOTCH Signaling Specifies a Transient Arterial-Type Hemogenic Endothelium that Gives Rise to Definitive-Type Hematopoiesis from Human Pluripotent Stem Cells
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Recently, we identified and characterized specific endothelial progenitors with varying hemogenic potential during human pluripotent stem cell differentiation. Based on these studies we established a platform on which we can manipulate NOTCH signaling on these subsets to elucidate the specific role of this signaling pathway during hemogenic endothelial specification, endothelial-to-hematopoietic transition, and definitive hematopoietic specification.
Overall design Manipulate NOTCH signaling during hemogenic endothelial specification, endothelial-to-hematopoietic transition, and definitive hematopoietic specification and expansion.
Contributor(s) Slukvin I, Uenishi G, Swanson S, Moskvin O
Citation(s) 29739946
Submission date Feb 17, 2017
Last update date Jul 25, 2021
Contact name Oleg Moskvin
Organization name University of Wisconsin-Madison
Street address 1220 Capitol Court
City Madison
State/province WI
ZIP/Postal code 53715
Country USA
Platforms (1)
GPL21290 Illumina HiSeq 3000 (Homo sapiens)
Samples (4)
GSM2494882 D4+1(DLL1 HE:DLL4-)+5(OP9) lin-CD34+CD43+CD45+
GSM2494883 D4+1(DLL1 HE:DLL4-)+5(OP9DLL4) lin-CD34+CD43+CD45+
GSM2494884 D4+1(DLL1 HE:DLL4+)+5(OP9DLL4) lin-CD34+CD43+CD45+
BioProject PRJNA375763
SRA SRP100165

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE95028_Gene_TPM_3samples.txt.gz 139.4 Kb (ftp)(http) TXT
GSE95028_Gene_counts_3samples.txt.gz 145.9 Kb (ftp)(http) TXT
GSE95028_RAW.tar 160.0 Kb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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