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Series GSE94947 Query DataSets for GSE94947
Status Public on Oct 31, 2017
Title RNA-seq of HDAC2-disrupted 293FT cells by CRISPR-Cas9
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary The transcriptional functions of HDAC1 and HDAC2 are largely viewed as repressive through their association in corepressor complexes, however, the unique functions and targets of HDAC2 are less well understood. We have utilized HDAC2-null cells to distinguish the role of HDAC2 in human cells and identify uniqye HDAC2 targets.
Overall design HDAC2-null 293FT cells were created via CRISPR-Cas9 targeting and analyzed by RNA-seq for differential expression.
Contributor(s) Somanath P, Klein RH, Knoepfler P
Citation(s) 28982113
Submission date Feb 15, 2017
Last update date May 15, 2019
Contact name Paul Knoepfler
Organization name UC Davis School of Medicine
Department Cell Biology and Human Anatomy
Lab Knoepfler
Street address 1 Shields Ave
City Davis
State/province CA
ZIP/Postal code 95616
Country USA
Platforms (1)
GPL21290 Illumina HiSeq 3000 (Homo sapiens)
Samples (12)
GSM2492288 293FT WT-1
GSM2492289 293FT WT-2
GSM2492290 293FT WT-3
BioProject PRJNA374887
SRA SRP099865

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SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE94947_HDAC2_rawcount.txt.gz 266.5 Kb (ftp)(http) TXT
GSE94947_WT_L14_EdgeR.txt.gz 42.9 Kb (ftp)(http) TXT
GSE94947_WT_L15_EdgeR.txt.gz 18.0 Kb (ftp)(http) TXT
GSE94947_WT_L5_EdgeR.txt.gz 43.7 Kb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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