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Series GSE94931 Query DataSets for GSE94931
Status Public on Sep 06, 2017
Title Gene expression changes in primary GBM neurosphere cultures after 24 hours of CDK7 inhibition
Organism Homo sapiens
Experiment type Expression profiling by array
Summary CDK7 controlls both global gene transcription and cell cycle progression. To see what global gene changes were occuring after application of THZ1 to GBM cells, we conducted the following microarray analyses.
Overall design Two distinct GBM neurosphere cell lines were treated in quadruplicate with DMSO vehicle or 200 nM of the irreversible CDK7 inhibitor THZ1. After 24 hours, total RNA was harvested from the samples and hybridised to the arrays.
Contributor(s) Greenall S, Johns T
Citation(s) 28504693
Submission date Feb 15, 2017
Last update date Jan 09, 2018
Contact name Sam Greenall
Organization name Hudson Institute of Medical Research
Department Centre for Cancer Research
Lab Oncogenic Signalling Laboratory
Street address 27-31 Wright Street
City Clayton
State/province VIC
ZIP/Postal code 3168
Country Australia
Platforms (1)
GPL17077 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
Samples (16)
GSM2492090 GBM6-V1
GSM2492091 GBM6-V2
GSM2492092 GBM6-V3
BioProject PRJNA374870

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE94931_RAW.tar 49.0 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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