GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE94730 Query DataSets for GSE94730
Status Public on Mar 28, 2017
Title The RNA helicase DDX39B regulates IL7R alternative splicing reducing the risk of Multiple Sclerosis
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Purpose: The goal of this study is to investigate the role of DDX39B in RNA splicing
Methods: RNA-Seq splicing analysis of HeLa cells with experimentally induced DDX39B expression knockdown
Overall design DDX39B expression is reduced in HeLa cells by siRNAs. Effects on alternative RNA splicing are compared between knockdown and control cells.
Contributor(s) Galarza-Muñoz G, Briggs FB, Evsyukova I, Schott-Lerner GO, Kennedy EM, Nyanhete T, Wang L, Bergamaschi L, Widen SG, Tomaras GD, Ko DC, Bradrick SS, Barcellos LF, Gregory SG, Garcia-Blanco MA
Citation(s) 28340352
Submission date Feb 09, 2017
Last update date May 15, 2019
Contact name Mariano Garcia-Blanco
Phone 409-772-2271
Organization name The University of Texas Medical Branch
Street address 301 University Blvd
City Galveston
ZIP/Postal code 77555
Country USA
Platforms (1)
GPL18460 Illumina HiSeq 1500 (Homo sapiens)
Samples (6)
GSM2481526 HeLa_NTC Replicate 1
GSM2481527 HeLa_DDX_3 Replicate 1
GSM2481528 HeLa_DDX_4 Replicate 1
BioProject PRJNA373878
SRA SRP099127

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource 16.3 Mb (ftp)(http) TAB
GSE94730_NS.vs.D11.vast-tools.0.2.1.pdf 2.4 Mb (ftp)(http) PDF 2.3 Mb (ftp)(http) TAB
GSE94730_NS.vs.D13.vast-tools.0.2.1.pdf 1.2 Mb (ftp)(http) PDF 2.3 Mb (ftp)(http) TAB
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap