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Series GSE94340 Query DataSets for GSE94340
Status Public on Jan 01, 2018
Title Expression data from skin biopsies in patients with systemic sclerosis treated with beta-catenin inhibitor (C82) and placebo
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Wnt signaling pathway is thought to have a role in skin fibrosis in Systemic slcerosis. This Randomized, Placebo-Controlled trial examines the effect of beta catenin inhibition on skin expression.
We used microarrays to explore gene expression changes in the C82 trial
 
Overall design Patietns with diffuse cutaneous systemic sclerosis had biopsis before treatment and at day 28.
 
Contributor(s) Mantero JC, Lafyatis R
Citation(s) 28807667
Submission date Jan 31, 2017
Last update date Dec 06, 2018
Contact name Julio C Mantero
Organization name Boston University School of Medicine
Department Rheumatology
Street address 72 E Concord St
City Boston
State/province MA
ZIP/Postal code 02118
Country USA
 
Platforms (1)
GPL571 [HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Samples (66)
GSM2473411 Patient 101 -skin - Placebo - Baseline
GSM2473412 Patient 105 -skin - C82 - Baseline
GSM2473413 Patient 105 -skin - Placebo - Baseline
Relations
BioProject PRJNA369403

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE94340_RAW.tar 119.2 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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