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Series GSE93793 Query DataSets for GSE93793
Status Public on Jul 24, 2017
Title Characterization of three Epithelial Ovarian Cancer cell lines resistant to cisplatin (mRNA).
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Epithelial ovarian cancer (EOC) represents the gynecologic cancer with the highest mortality rate. Despite a high initial response to chemotherapy, the majority of patients with advanced EOC relapses and subsequently develops chemoresistance that results in treatment failure and death of the patient. AIM: we have generated an isogenic model of PT-resistance in a panel of 3 EOC cell lines. Gene Expression Profile (GEP) was used to identify new molecular pathawy that regulate chemoresistance.
Overall design GEP experiments were performed in 3 Epithelian Ovarian Cancer cell lines Platinum-resistant vs their parental, with Agilent platform. Bioinformatics analyses were performed by Gene Springs
Contributor(s) Sonego M, Pellizzari I, Bomben R, Baldassarre G
Citation(s) 28769043
Submission date Jan 18, 2017
Last update date Aug 25, 2019
Contact name Riccardo Bomben
Phone +39 0434 659718
Organization name CRO Aviano
Department D-RT
Lab Clinical and Experimental Onco Hematology Unit
Street address Via Franco Gallini 2
City Aviano
ZIP/Postal code 33080
Country Italy
Platforms (1)
GPL17077 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
Samples (12)
GSM2462175 OVSAHO MI-res1
GSM2462176 OVSAHO MI-res2
GSM2462177 MDAH MI-res1
This SubSeries is part of SuperSeries:
GSE93795 Characterization of three Epithelial Ovarian Cancer cell lines resistant to cisplatin.
BioProject PRJNA362360

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE93793_RAW.tar 149.6 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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