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Series GSE92590 Query DataSets for GSE92590
Status Public on Jan 24, 2017
Title Simultaneous transcriptional and epigenomic profiling from specific cell types within heterogeneous tissues in vivo
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Summary This study introduces “NuTRAP”, a transgenic mouse that allows simultaneous isolation of cell type-specific translating mRNA and chromatin from complex tissues
Using NuTRAP, we successfully characterize gene expression and epigenomic states of various adipocyte populations in vivo,
To demonstrate general usefulness, we chateraterize histone states of in vivo hepatocytes.
Overall design We demonstrate the robustness of NuTRAP-based ChIP-seq by performing titration experiments
Contributor(s) Roh H, Rosen E
Citation(s) 28122230
Submission date Dec 19, 2016
Last update date May 15, 2019
Contact name Evan Rosen
Organization name Beth Israel Deconess Medical Center
Department Endocrinology
Lab Rosen Lab
Street address 3 Blackfan Cir
City Boston
State/province MA
ZIP/Postal code 02215
Country USA
Platforms (3)
GPL16417 Illumina MiSeq (Mus musculus)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
GPL19057 Illumina NextSeq 500 (Mus musculus)
Samples (36)
GSM2433080 Input-rep1
GSM2433081 Input-rep2
GSM2433082 TRAP-rep1
BioProject PRJNA358099
SRA SRP095371

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE92590_RAW.tar 5.6 Gb (http)(custom) TAR (of BW)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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