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Series GSE90929 Query DataSets for GSE90929
Status Public on Aug 17, 2017
Title Transcriptional changes in the primary somatosensory cortex upon sensory deprivation
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Experience-dependent plasticity (EDP) is essential for anatomical and functional maturation of sensory circuits during development and can be readily studied is the rodent barrel cortex. Using this model we aimed to uncover changes on the transcriptome level and applied RNA sequencing upon altered sensory experience in juvenile mice in a cortical column and layer specific manner. From column- and layer-specific barrel cortical tissue, high quality RNA was purified and sequenced. The current dataset entails an average of 50 million paired-end reads per sample, 75 base pairs in length.
Overall design Wild type mice were deprived of their C-row whiskers from P12 until P23-P24, after which acute brain slices were prepared and tissues were excised from L2/3 and L4 from specific barrel columns. RNA isolated from these tissue sections was then subjected to RNA-sequencing.
Contributor(s) Kole K, Komuro Y, Provaznik J, Pistolic J, Benes V, Tiesinga P, Celikel T
Citation(s) 29020745
Submission date Dec 06, 2016
Last update date May 15, 2019
Contact name Koen Kole
Organization name Donders Institute for Brain Cognition and Behaviour
Department Neurophysiology
Street address Heyendaalsweg 135
City Nijmegen
ZIP/Postal code 6525 EN
Country Netherlands
Platforms (1)
GPL19057 Illumina NextSeq 500 (Mus musculus)
Samples (32)
GSM2417709 Control_L2/3_1
GSM2417710 Control_L2/3_2
GSM2417711 Control_L2/3_3
BioProject PRJNA356396
SRA SRP094627

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Supplementary file Size Download File type/resource
GSE90929_Genecounts_Colourcoded.xlsx.gz 4.5 Mb (ftp)(http) XLSX
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Raw data are available in SRA

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