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Series GSE90557 Query DataSets for GSE90557
Status Public on Mar 07, 2019
Title Genome-wide maps of chromatin state in neural stem/progenitor cells (NSC) from mouse neonatal forebrain [ChIA-PET]
Organism Mus musculus
Experiment type Other
Summary We report the application of single-molecule-based DNA sequencing technology for high-throughput profiling of long-range chromatin interactions in Sox2-deleted and wild type NSC, by improved ChIA-PET procedure (in situ ChIA-PET) with antiRNApolII antibodies. By obtaining sequences from chromatin immunoprecipitated DNA, we generated genome-wide maps of inter-molecular ligated DNA representing long-range interactions in chromatin.
Overall design Analysis of RNApolII-mediated long-range interactions in chromatin of Sox2-deleted and wild type neural stem/progenitor cells (NSC) cultured from neonatal mouse brains.
Contributor(s) Wong C, Favaro R, Tjong H, Pagin M, Zhu Y
Citation(s) 30849367
Submission date Nov 26, 2016
Last update date May 21, 2019
Contact name Federico Zambelli
Organization name University of Milan
Department Department of Biosciences
Street address Via Giovanni Celoria 26
City Milano
ZIP/Postal code 20133
Country Italy
Platforms (2)
GPL9250 Illumina Genome Analyzer II (Mus musculus)
GPL19057 Illumina NextSeq 500 (Mus musculus)
Samples (5)
GSM2406790 RNApolII ChIA-PET, Sox2-deleted cultured NSC
GSM3143597 RNApolII in situ ChIA-PET, Sox2-deleted cultured NSC (TR2)
GSM3143598 RNApolII in situ ChIA-PET, Sox2-deleted cultured NSC (TR3)
This SubSeries is part of SuperSeries:
GSE90561 Sox2 is required for functional chromatin connectivity in brain-derived neural stem cells.
BioProject PRJNA355015
SRA SRP093983

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE90557_RAW.tar 12.9 Mb (http)(custom) TAR (of BEDPE, TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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