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Series GSE89794 Query DataSets for GSE89794
Status Public on Nov 14, 2016
Title Differential gene expression analysis of WT and p190-B-/- HSC after bone marrow transplantation
Organism Mus musculus
Experiment type Expression profiling by array
Summary The overall goals are these experiments are to identify genes and pathways that are critical for hematopoietic stem cell functions during bone marrow regeneration after transplantation. We have found that loss of expression of p190-B RhoGAP, a negative regulator of RhoGTPase, enhances HSC long-term engraftment. Hence, we used microarray analysis to compare gene exprssion profile of WT and p190-B-/- HSC after transplantation.
 
Overall design Expression profiles of mRNA in HSCs from WT and p190-B-/- transplanted mice
 
Contributor(s) Hinge A, Aronow B, Filippi M
Citation(s) 28176763
Submission date Nov 13, 2016
Last update date Jun 26, 2019
Contact name Marie-Dominique Filippi
E-mail(s) marie-dominique.filippi@cchmc.org
Phone 513-636-0991
Organization name Cincinnati Children's Research Foundation
Department Experimental Hematology and Cancer Biology
Street address 3333 Burnet Av
City Cincinnati
State/province OH
ZIP/Postal code 45229
Country USA
 
Platforms (1)
GPL10333 Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Feature Number version)
Samples (6)
GSM2389003 BM_1_WT_Transplant
GSM2389004 BM_2_WT_Transplant
GSM2389005 BM_3_WT_Transplant
Relations
BioProject PRJNA353313

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE89794_RAW.tar 60.7 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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