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Series GSE89447 Query DataSets for GSE89447
Status Public on Dec 31, 2017
Title The Gene Expression Study (GEP) was based on a cohort of 27 MCL cases enrolled in the Fondazione Italiana Linfomi (FIL)-MCL-0208 randomized Italian clinical trial.
Organism Homo sapiens
Experiment type Expression profiling by array
Summary The aggressive clinical behavior of mantle cell lymphoma (MCL) is attributed to specific genetic and molecular mechanisms involved in its pathogenesis, mainly the t(11;14)(q13;q32) traslocation and cyclin D1 (CCND1) overexpression. Nevertheless, evidence of a certain degree of clinical/biological heterogeneity has been disclosed by gene expression profile (GEP) and (immuno)genetic/immunohistochemistry studies. AIM: To use a GEP approach to identify MCL subsets with peculiar clinical/biological features in the context of of MCL patients treated homogeneously with an autologous transplantation-based program.
 
Overall design GEP experiments were performed in 27 cases, with Agilent platform. Bioinformatics analyses were performed by Gene Springs
 
Contributor(s) Bomben R, D'Agaro T, Bomben R, Gattei V
Citation(s) 29472356
Submission date Nov 02, 2016
Last update date Jul 29, 2019
Contact name Riccardo Bomben
E-mail(s) rbomben@cro.it
Phone +39 0434 659718
Organization name CRO Aviano
Department D-RT
Lab Clinical and Experimental Onco Hematology Unit
Street address Via Franco Gallini 2
City Aviano
ZIP/Postal code 33080
Country Italy
 
Platforms (1)
GPL17077 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
Samples (27)
GSM2372334 MCL_102
GSM2372335 MCL_205
GSM2372336 MCL_707
Relations
BioProject PRJNA352233

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE89447_RAW.tar 335.6 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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