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Series GSE89173 Query DataSets for GSE89173
Status Public on Dec 31, 2018
Title Genome-wide transcriptomic and epigenomic study of DHA in rat hypothalamus and hippocampus [RNA-seq]
Organism Rattus norvegicus
Experiment type Expression profiling by high throughput sequencing
Summary To investigate the effects of DHA (an omega-3 fatty acid) on brain dysfunction and metabolic disorders by sequencing the transcriptome (RNA-Seq) and epigenome (RRBS) in the hypothalamus and hippocampus of male SD rats.
Overall design Male Sprague Dawley (SD) rats of 2 months old were randomly assigned to an omega-3 fatty acid diet containing DHA or a regular chow diet without DHA supplement for six weeks. The rats were sacrificed by decapitation. Hypothalamus and hippocampus were dissected out, flash frozen, and stored at -70 C for later transcriptome and DNA methylome sequencing experiments. All experiments were performed in accordance with the United States National Institutes of Health Guide for the Care and Use of Laboratory Animals and were approved by the University of California at Los Angeles Chancellor's Animal Research Committee.
Contributor(s) Meng Q, Gomez-Pinilla F, Yang X
Citation(s) 33063454
Submission date Oct 25, 2016
Last update date Apr 27, 2023
Contact name Xia Yang
Organization name UCLA
Street address 610 Charles E. Young Dr. East
City Los Angeles
State/province CA
ZIP/Postal code 90095
Country USA
Platforms (1)
GPL14844 Illumina HiSeq 2000 (Rattus norvegicus)
Samples (7)
GSM1581142 DHA_hippocampus_rep1 [RNA-seq]
GSM1581143 DHA_hippocampus_rep2 [RNA-seq]
GSM1581144 DHA_hippocampus_rep3 [RNA-seq]
This SubSeries is part of SuperSeries:
GSE89176 Genome-wide transcriptomic and epigenomic study of DHA in rat hypothalamus and hippocampus
BioProject PRJNA352569
SRA SRP092943

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Supplementary file Size Download File type/resource
GSE89173_Hippocampus_fpkm_processed.txt.gz 377.9 Kb (ftp)(http) TXT
GSE89173_Hypothalamus_fpkm_processed.txt.gz 311.2 Kb (ftp)(http) TXT
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