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Series GSE87548 Query DataSets for GSE87548
Status Public on Jan 01, 2017
Title Layer-specific ATAC-seq of the neurons of adult mouse visual cortex defined by Cre-driver lines
Organism Mus musculus
Experiment type Other
Summary Mammalian cortex is a laminar structure, with each layer composed of a characteristic set of cell types with different morphological, electrophysiological, and connectional properties. Here, we define chromatin accessibility landscapes of major, layer-specific excitatory classes of neurons, and compare them to each other and to inhibitory cortical neurons using the Assay for Transposase-Accessible Chromatin with high-throughput sequencing (ATAC-seq). We surveyed five Cre-reporter-labeled mouse cell lines using ATAC-Seq of 500-cell populations.
Overall design ATAC-Seq of 500-cell populations
Contributor(s) Gray LT, Yao Z, Nguyen TN, Kim TK, Zeng H, Tasic B
Citation(s) 28112643
NIH grant(s)
Grant ID Grant title Affiliation Name
R01 DA036909 Temporal, cell type- and locus-specific epigenetic control in transgenic mice ALLEN INSTITUTE TASIC
Submission date Oct 03, 2016
Last update date May 15, 2019
Contact name Lucas T Gray
Organization name Allen Institute for Brain Science
Department Molecular Genetics
Lab Tasic
Street address 615 Westlake Ave N
City Seattle
State/province WA
ZIP/Postal code 98109
Country USA
Platforms (2)
GPL16417 Illumina MiSeq (Mus musculus)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (20)
GSM2333632 Cux2_L2/3_500cell_rep1
GSM2333633 Cux2_L2/3_500cell_rep2
GSM2333634 Cux2_L2/3_500cell_rep3
BioProject PRJNA345167
SRA SRP090744

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Supplementary file Size Download File type/resource
GSE87548_RAW.tar 33.9 Mb (http)(custom) TAR (of BROADPEAK, NARROWPEAK)
GSE87548_merged_peaks.bed.gz 1.9 Mb (ftp)(http) BED
GSE87548_merged_peaks.tmmScores.txt.gz 10.2 Mb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file
Processed data are available on Series record

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