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Series GSE86810 Query DataSets for GSE86810
Status Public on Apr 05, 2017
Title Genome-wide histone modification profiling in endometriosis cells
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary We show that knocking down ARID1A in an immortalized endometriosis cell line leads to phenotypic changes in vitro. Additionally, we find strong increases in the active H3K27ac mark in promoter regions but decrease of H3K27ac at potential enhancers.
Overall design Examination of 4 different histone modifications in endometriosis control and ARID1A knockdown cell lines.
Contributor(s) Lakshminarasimhan R, Andreu-Vieyra C, Lawrenson K, Duymich CE, Gayther SA, Liang G, Jones PA
Citation(s) 28483516
Submission date Sep 12, 2016
Last update date May 15, 2019
Contact name Ranjani Lakshminarasimhan
Phone 3238650736
Organization name University of Southern California
Department Urology
Lab Jones/Liang
Street address 1441 Eastlake ave NOR7336
City Los Angeles
State/province California
ZIP/Postal code 90033
Country USA
Platforms (2)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
Samples (18)
GSM2308931 SCR_rep1_H3K4me1
GSM2308932 SCR_rep1_H3K4me3
GSM2308933 SCR_rep1_H3K27me3
BioProject PRJNA342603
SRA SRP089677

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Supplementary file Size Download File type/resource
GSE86810_H3K27ac.peaklist.txt.gz 1.0 Mb (ftp)(http) TXT
GSE86810_H3K27me3.peaklist.txt.gz 1.3 Mb (ftp)(http) TXT
GSE86810_H3K4me1.peaklist.txt.gz 1.9 Mb (ftp)(http) TXT
GSE86810_H3K4me3.peaklist.txt.gz 501.0 Kb (ftp)(http) TXT
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Raw data are available in SRA

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