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Series GSE86232 Query DataSets for GSE86232
Status Public on Feb 13, 2018
Title ERK potentiates transactivation and oncogenic function of ERG by phosphorylation induced dissociation of PRC2 complex
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Expression profiling by high throughput sequencing
Summary ERK activates ERG-mediated prostate cancer specific gene expression program by phopshorylation induced dissociation of PRC2 complex
Overall design ChIP-Seq of transcription factor ERG and its co-repressor EZH2
RNA-seq of polyA selected RNA from RWPE1 cells expressing either empty vector, ERG-WT, ERG-S96A and ERG-S96E

Contributor(s) Kedage V, Hollenhorst PC
Citation(s) 28887309, 34314419
Submission date Aug 30, 2016
Last update date Aug 11, 2021
Contact name Vivekananda Kedage
Organization name Indiana University
Street address 1001 E. third Street
City Bloomington
State/province IN
ZIP/Postal code 47405
Country USA
Platforms (1)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
Samples (20)
GSM2298873 ERG-ChIP_RWPE1-ERG(S96A).fastq.gz
GSM2298874 EZH2-ChIP_RWPE1-Vector.fastq.gz
GSM2298875 EZH2-ChIP_RWPE1-ERG(WT).fastq.gz
BioProject PRJNA340977
SRA SRP083756

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE86232_Differential_gene_expression.xlsx 8.9 Mb (ftp)(http) XLSX
GSE86232_RAW.tar 330.0 Kb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file
Processed data are available on Series record

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