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Series GSE86153 Query DataSets for GSE86153
Status Public on Apr 27, 2017
Title Identification of extensive cellular diversity and maturation of active neuronal networks in long-term cultures of human brain organoids
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary We analyzed gene expression in over 80,000 individual cells isolated from 31 human whole-brain organoids that has developed for 3-6 months. We find that organoids can generate a broad diversity of cells, which we show are related to known endogenous classes, including subpopulations of neurons and progenitors of the cerebral cortex
Overall design Single cell Droplet sequencing of human cerebral organoid
Contributor(s) Quadrato G, Nguyen T, Macosko EZ, Sherwood JL, Berger D, Maria N, Scholvin J, Goldman M, Kinney J, Boyden E, Lichtman J, Williams ZM, McCarroll SA, Arlotta P
Citation(s) 28445462
Submission date Aug 28, 2016
Last update date May 15, 2019
Contact name Paola Arlotta
Organization name Harvard University
Department Stem Cell & Regenerative Biology
Street address 7 Divinity Avenue
City Cambridge
State/province MA
ZIP/Postal code 02138
Country USA
Platforms (1)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
Samples (2)
GSM2295945 Organoids at six month age
GSM2295946 Organoids at three month age
BioProject PRJNA340373
SRA SRP083140

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE86153_RAW.tar 899.8 Mb (http)(custom) TAR (of CSV)
GSE86153_organoid_names.txt.gz 289 b (ftp)(http) TXT
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Raw data are available in SRA
Processed data provided as supplementary file

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