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Series GSE85462 Query DataSets for GSE85462
Status Public on Oct 19, 2016
Title Escape from X-Inactivation Tumor Suppressor (EXITS) genes contribute to sex bias
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary In this manuscript, we described male-biased mutations in chrX genes in cancer. In this RNA-seq experiment we tested the transcriptional consequences of shRNA knockdown of one of those genes, CNKSR2
Overall design Murine NIH 3T3 cells were infected with and selected for expression of lentiviruses expressing shRNAs targeting Cnksr2 (2 independent shRNA sequences) or a control shRNA (targeting RFP, a gene not present in these cells). Each was performed in biological triplicate independent cultures for n=9 total samples
Contributor(s) Lane AA
Citation(s) 27869828
Submission date Aug 11, 2016
Last update date May 15, 2019
Contact name Andrew Lane
Phone 617-632-4589
Organization name Dana-Farber Cancer Institute
Street address 450 Brookline Ave
City Boston
State/province MA
ZIP/Postal code 02215
Country USA
Platforms (1)
GPL19057 Illumina NextSeq 500 (Mus musculus)
Samples (9)
GSM2267346 shControl_1
GSM2267347 shControl_2
GSM2267348 shControl_3
BioProject PRJNA338593
SRA SRP081265

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE85462_FPKM_matrix.xlsx 1.0 Mb (ftp)(http) XLSX
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Raw data are available in SRA
Processed data are available on Series record

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