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Series GSE85315 Query DataSets for GSE85315
Status Public on Mar 09, 2017
Title Genome-wide changes in H3K4me3 after MEN1 silencing in MCF-7 cells
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary We performed ChIP-seq using H3K4me3 antibodies in MCF-7 cells after induction of small hairpin RNA's directed at the MEN1 mRNA or a control sequence. We demonstrate that at a selected group of loci H3K4me3 is affected by MEN1 silencing.
Overall design Comparison of genome-wide H3K4me3 binding after ShMEN1 induction vs ShCtrl, in duplicate.
Contributor(s) Dreijerink KM, Groner AC
Citation(s) 28273452
Submission date Aug 08, 2016
Last update date May 15, 2019
Contact name Koen M.A. Dreijerink
Organization name Dana-Farber Cancer Institute
Department Medical Oncology
Street address 450 Brookline Avenue
City Boston
State/province MA
ZIP/Postal code 02215
Country USA
Platforms (2)
GPL15520 Illumina MiSeq (Homo sapiens)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
Samples (6)
GSM2264588 MCF7_H3K4me3_ShCtrl_1
GSM2264589 MCF7_H3K4me3_ShCtrl_2
GSM2264590 MCF7_input_ShCtrl
BioProject PRJNA338157
SRA SRP081088

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Supplementary file Size Download File type/resource
GSE85315_RAW.tar 355.4 Mb (http)(custom) TAR (of BED, BW)
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Raw data are available in SRA
Processed data provided as supplementary file

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