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Series GSE83990 Query DataSets for GSE83990
Status Public on Feb 16, 2018
Title Zone dependent distinctive gene expression profile of the normal human liver tissue
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary The regulatory mechanisms that shapes the hepatic zonation is not well understood. In addition, the concept and significance of of hepatic zonation is well established in rodens, however, its relavence to human liver biology remain elusive. We conducted a comprehensive transcriptome analysis of each zonation within normal human liver vis Laser Capture Microdissection approach. Here, we report a poly A RNA sequencing data of the individual zone of liver tissue as well as the whole liver of the corresponding subjects.
Overall design The RNA samples were collected from each zone within hepatic lobule by a Laser Captured Microdissection approach. This study examined the gene expression profile in each zone of the normal human liver.
Contributor(s) Saito T, Li M
Citation(s) 29244788
Submission date Jul 04, 2016
Last update date May 15, 2019
Contact name Meng Li
Organization name University of Southern California
Street address 2003 Zonal Avenue
City Los Angeles
State/province CA
ZIP/Postal code 90089-0110
Country USA
Platforms (1)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
Samples (12)
GSM2224921 LM1-WL
GSM2224922 LM1-Z1
GSM2224923 LM1-Z2
BioProject PRJNA327753
SRA SRP077872

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE83990_Saito_LiverZonation_NormalizedReads.txt.gz 1.6 Mb (ftp)(http) TXT
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Processed data are available on Series record

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