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Status |
Public on Sep 21, 2017 |
Title |
Effect of vaccine administration routes on responses to a Bordetella pertussis outer membrane vesicle vaccine - lung |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
Pulmonary immunization with an outer membrane vesicle pertussis vaccine led to improved protection and induction of a completely distinct immune response compared to subcutaneous administration. These adaptive responses were linked to early local and systemic signatures on the transcriptome level.
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Overall design |
23 arrays, including replicates and controls, analyzed on Affymetrix genechips
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Contributor(s) |
Pennings J, Raeven R, Brummelman J |
Citation(s) |
28930286 |
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Submission date |
Jun 22, 2016 |
Last update date |
Sep 23, 2017 |
Contact name |
Jeroen Pennings |
E-mail(s) |
Jeroen.Pennings@rivm.nl
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Phone |
+31 88 689 2214
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Organization name |
Natl. Inst. Public Health & Environment
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Street address |
A. van Leeuwenhoeklaan 9
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City |
Bilthoven |
ZIP/Postal code |
3721MA |
Country |
Netherlands |
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Platforms (1) |
GPL21382 |
[HT_MG-430_PM] Affymetrix HT MG-430 PM Array Plate [CDF: HTMG430PM_Mm_ENTREZG, Brainarray version 19] |
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Samples (23)
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This SubSeries is part of SuperSeries: |
GSE83604 |
Effect of vaccine administration routes on responses to a Bordetella pertussis outer membrane vesicle vaccine |
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Relations |
BioProject |
PRJNA326474 |