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Series GSE81831 Query DataSets for GSE81831
Status Public on May 24, 2017
Title Gene expression signatures for entecavir treated HepG2.2.15 cells compared to entecavir untreated HepG2.2.15 cells
Organism Homo sapiens
Experiment type Expression profiling by array
Summary To further analyze the gene expression profile regulated by entecavir, we employed whole genome microarray expression profiling as a discovery platform to identify the differentially expressed genes. Human hepatocellular carcinoma cell lines HepG2.2.15 cells were treated for 48 hr with 10 μmol/L entecavir or 0μmol/L entecavir(control samples) in vitro. The differentially expressed genes including all detected and normalized signal more than 8 were selected and 30 upregulated- and downregulated- genes were identified between 10μmol/L dose and control samples.Afterwards, the differentially-expressed genes were analyzed using KEGG database ( and none of 30 genes were related to HBV infection-related molecular interaction network were identified.
Overall design Entecavir-regulated genes in HepG2.2.15 cells was measured at 48 hours after exposure to doses of 0 μmol/L, 10 μmol/L.
Contributor(s) Liu Y, Yao W, Xu D
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Submission date May 24, 2016
Last update date Jan 09, 2018
Contact name dongping xu
Organization name Research Center for Clinical and Translational Medicine, Beijing 302 Hospital, Beijing
Street address #100 Xisihuan Middle Road, Beijing
City Beijing
ZIP/Postal code 100039
Country China
Platforms (1)
GPL17077 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
Samples (2)
GSM2176432 invitroCells_48hr_0 μmol/L_rep1
GSM2176433 invitroCells_48hr_10 μmol/L_rep1
BioProject PRJNA322658

Download family Format
SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE81831_RAW.tar 24.8 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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