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Series GSE81803 Query DataSets for GSE81803
Status Public on Aug 18, 2017
Title RNA-sequencing in WT and Fmr1-/- (KO) neurons treated with Jq1 and THZ
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Widespread epigenetic disruptions in FXS mice leads to transcriptional changes that likely contribute to the neuronal phenotpyes underlying FXS.
Overall design 7DIV cultured cortical neurons from WT or Fmr1 KO mice were treated for 24 hours with vehicle, Jq1, or THZ, performed in triplicate.
Contributor(s) Korb E
Citation(s) 28823556
NIH grant(s)
Grant ID Grant title Affiliation Name
K99 MH111836 The histone code of neuronal function and dysfunction THE ROCKEFELLER UNIVERSITY Erica Megan Korb
Submission date May 23, 2016
Last update date May 15, 2019
Contact name Erica Korb
Organization name University of Pennsylvania
Lab Korb Lab
Street address 3400 Civic Center Boulevard
City Philadelphia
State/province PENNSYLVANIA
ZIP/Postal code 19104
Country USA
Platforms (1)
GPL19057 Illumina NextSeq 500 (Mus musculus)
Samples (18)
GSM2175747 WT_dmso_n1
GSM2175748 WT_dmso_n2
GSM2175749 WT_dmso_n3
This SubSeries is part of SuperSeries:
GSE81912 Fragile X Syndrome causes epigenetic disruptions treatable with BET inhibitor Jq1
BioProject PRJNA322630
SRA SRP075646

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SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE81803_RAW.tar 738.3 Mb (http)(custom) TAR (of TDF)
GSE81803_WTvKO.deseq2.csv.gz 869.3 Kb (ftp)(http) CSV
GSE81803_counttab.txt.gz 835.3 Kb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file
Processed data are available on Series record

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