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Series GSE81466 Query DataSets for GSE81466
Status Public on Nov 07, 2016
Title SOX7 supresses the expression of RUNX1 target genes during EHT
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary The molecular mechanisms regulating endothelial to hematopoietic transition (EHT) of hemogenic endothelium (HE) are poorly understood. Here we profile the transcriptional changes resulting from SOX7 overexpression during EHT
Overall design FLK1+ cells were sorted from day 3.5 iSox7 EBs and cultured in liquid blast media for 48hours. Dox was added for 6, 12 and 24 hours to induce SOX7 expression, before samples were harvested for RNAseq.
Contributor(s) Lilly A, Fadlullah MZ, Kouskoff V
Citation(s) 27802172
Submission date May 16, 2016
Last update date May 15, 2019
Contact name Andrew Joshua Lilly
Organization name CRUK Manchester Institute
Department Stem Cell Haematopoiesis
Street address Wilmslow Road
City Manchester
ZIP/Postal code M20 4BX
Country United Kingdom
Platforms (1)
GPL19057 Illumina NextSeq 500 (Mus musculus)
Samples (12)
GSM2152828 NoDox_6hr_rep1
GSM2152829 Dox_6hr_rep1
GSM2152830 NoDox_12hr_rep1
BioProject PRJNA321724
SRA SRP075208

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE81466_NoDox12h_vs_Dox12h.xlsx.gz 1.4 Mb (ftp)(http) XLSX
GSE81466_NoDox24h_vs_Dox24h.xlsx.gz 1.4 Mb (ftp)(http) XLSX
GSE81466_NoDox6h_vs_Dox6h.xlsx.gz 1.0 Mb (ftp)(http) XLSX
GSE81466_RPKM_allGenes.txt.gz 2.7 Mb (ftp)(http) TXT
GSE81466_rawReadCount.txt.gz 1.1 Mb (ftp)(http) TXT
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Raw data are available in SRA

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