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Series GSE80593 Query DataSets for GSE80593
Status Public on Jun 14, 2016
Title Genome-wide KDM5A occupancy after MK2206/DMSO treatment of T47D cells
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary We perfomed ChIP-seq using KDM5A antibodies in T47D cells after 24 hour treatment with the AKT inhibitor MK2206 or DMSO. We show that the cistrome of the H3K4 demethylase KDM5A is affected by AKT inhibition.
Overall design Comparison of genome-wide KDM5A binding after AKT inhibition vs vehicle
Contributor(s) Dreijerink K, Groner A, Spangle J
Citation(s) 27292631
Submission date Apr 22, 2016
Last update date May 15, 2019
Contact name Koen M.A. Dreijerink
Organization name Dana-Farber Cancer Institute
Department Medical Oncology
Street address 450 Brookline Avenue
City Boston
State/province MA
ZIP/Postal code 02215
Country USA
Platforms (1)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
Samples (2)
GSM2131193 T47D_DMSO_KDM5A
GSM2131194 T47D_MK2206_KDM5A
This SubSeries is part of SuperSeries:
GSE80594 PI3K/AKT signaling regulates H3K4 methylation in breast cancer
BioProject PRJNA319400
SRA SRP073744

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Supplementary file Size Download File type/resource
GSE80593_RAW.tar 713.1 Mb (http)(custom) TAR (of BED, BW)
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Raw data are available in SRA
Processed data provided as supplementary file

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