|
| Status |
Public on Jun 14, 2016 |
| Title |
Genome-wide H3K4me3 after MK2206/DMSO treatment of T47D cells |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We perfomed ChIP-seq using H3K4me3 antibodies in T47D cells after 24 hour treatment with the AKT inhibitor MK2206 or DMSO. We demonstrate that at a selected group of loci H3K4me3 is affected by AKT inhibition.
|
| |
|
| Overall design |
Comparison of genome-wide H3K4me3 binding after AKT inhibition vs vehicle
|
| |
|
| Contributor(s) |
Dreijerink K, Groner A, Spangle J |
| Citation(s) |
27292631 |
| Submission date |
Apr 22, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Koen M.A. Dreijerink |
| E-mail(s) |
koendreijerink@yahoo.com
|
| Organization name |
Dana-Farber Cancer Institute
|
| Department |
Medical Oncology
|
| Street address |
450 Brookline Avenue
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02215 |
| Country |
USA |
| |
|
| Platforms (2) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
|
| Samples (6)
|
|
| This SubSeries is part of SuperSeries: |
| GSE80594 |
PI3K/AKT signaling regulates H3K4 methylation in breast cancer |
|
| Relations |
| BioProject |
PRJNA319401 |
| SRA |
SRP073742 |
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