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Series GSE80592 Query DataSets for GSE80592
Status Public on Jun 14, 2016
Title Genome-wide H3K4me3 after MK2206/DMSO treatment of T47D cells
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary We perfomed ChIP-seq using H3K4me3 antibodies in T47D cells after 24 hour treatment with the AKT inhibitor MK2206 or DMSO. We demonstrate that at a selected group of loci H3K4me3 is affected by AKT inhibition.
Overall design Comparison of genome-wide H3K4me3 binding after AKT inhibition vs vehicle
Contributor(s) Dreijerink K, Groner A, Spangle J
Citation(s) 27292631
Submission date Apr 22, 2016
Last update date May 15, 2019
Contact name Koen M.A. Dreijerink
Organization name Dana-Farber Cancer Institute
Department Medical Oncology
Street address 450 Brookline Avenue
City Boston
State/province MA
ZIP/Postal code 02215
Country USA
Platforms (2)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
Samples (6)
GSM2131187 T47D_DMSO_H3K4me3_24
GSM2131188 T47D_DMSO_H3K4me3_48
GSM2131189 T47D_DMSO_H3K4me3_72
This SubSeries is part of SuperSeries:
GSE80594 PI3K/AKT signaling regulates H3K4 methylation in breast cancer
BioProject PRJNA319401
SRA SRP073742

Download family Format
SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE80592_RAW.tar 688.9 Mb (http)(custom) TAR (of BED, BW)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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