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Series GSE79572 Query DataSets for GSE79572
Status Public on Sep 23, 2016
Title Candidate genes and pathways downstream of PAX8 involved in ovarian high-grade serous carcinoma
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Our goal was to identify candidate genes and pathways regulated by PAX8 that could be additional targets for the therapy of ovarian carcinoma. To reach this aim, we have determined the molecular profiles of ovarian cancer cells and in parallel of Fallopian tube epithelial cells by mean of a silencing approach followed by an RNA-seq analysis
Overall design Comparison of the transcriptome in normal Fallopian tube secretory epithelial cells and ovarian cancer cells with and without PAX8 silencing
Contributor(s) de Cristofaro T, Di Palma T, Soriano A, Monticelli A, Affinito O, Cocozza S, Zannini M
Citation(s) 27259239
Submission date Mar 24, 2016
Last update date May 15, 2019
Contact name Stella Zannini
Organization name CNR IEOS
Street address Via Pansini 5
City Naples
ZIP/Postal code 80131
Country Italy
Platforms (1)
GPL18460 Illumina HiSeq 1500 (Homo sapiens)
Samples (12)
GSM2098470 WT SKOV3 rep1
GSM2098471 PAX8-KO SKOV-3 rep1
GSM2098472 WT SKOV3 rep2
BioProject PRJNA316212
SRA SRP072282

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SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE79572_RAW.tar 9.0 Mb (http)(custom) TAR (of TXT)
GSE79572_WT_vs_PAX8-KO_FT194_cuffdiff_genes.xls.gz 539.0 Kb (ftp)(http) XLS
GSE79572_WT_vs_PAX8-KO_SKOV3_cuffdiff_genes.xls.gz 535.9 Kb (ftp)(http) XLS
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file
Processed data are available on Series record

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