|
| Status |
Public on Apr 19, 2016 |
| Title |
Loss of Ezh2 cooperates with Jak2V617F in the development of myelofibrosis in a mouse model of myeloproliferative neoplasm |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
This SuperSeries is composed of the SubSeries listed below.
|
| |
|
| Overall design |
Refer to individual Series
|
| |
|
| Citation(s) |
27081096 |
| Submission date |
Mar 22, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Golam Mohi |
| E-mail(s) |
mohim@upstate.edu
|
| Organization name |
SUNY Upstate Medical University
|
| Department |
Pharmacology
|
| Street address |
766 Irving Avenue
|
| City |
Syracuse |
| State/province |
New York |
| ZIP/Postal code |
13210 |
| Country |
USA |
| |
|
| Platforms (2) |
| GPL16570 |
[MoGene-2_0-st] Affymetrix Mouse Gene 2.0 ST Array [transcript (gene) version] |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (12)
|
| GSM2087917 |
MxCre Jak2VF/+ LT-HSC, biological rep1 |
| GSM2087918 |
MxCre Jak2VF/+ LT-HSC, biological rep2 |
| GSM2087919 |
MxCre Jak2VF/+ LT-HSC, biological rep3 |
| GSM2087920 |
MxCre Jak2VF/+ EZH2-/- LT-HSC, biological rep1 |
| GSM2087921 |
MxCre Jak2VF/+ EZH2-/- LT-HSC, biological rep2 |
| GSM2087922 |
MxCre Jak2VF/+ EZH2-/- LT-HSC, biological rep3 |
| GSM2091489 |
WT_H3K27me3 ChIP-seq |
| GSM2091490 |
MxCre Jak2VF/+_H3K27me3 ChIP-seq |
| GSM2091491 |
MxCre Jak2VF/+ EZH2-/-_H3K27me3 ChIP-seq |
|
| This SuperSeries is composed of the following SubSeries: |
| GSE79198 |
Gene expression data from long term hematopoietic stem cells (LT-HSC, Lin-Sca-1+c-kit+CD34-CD135-) isolated from control, MxCre Jak2VF/+ and MxCre Jak2VF/+ EZH2-/- mice |
| GSE79319 |
H3K27me3 ChIP-sequencing on LSK (Lin-Sca-1+c-kit+) cells isolated from control, MxCre Jak2VF/+ and MxCre Jak2VF/+ EZH2-/- mice |
|
| Relations |
| BioProject |
PRJNA315946 |
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