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Series GSE78850 Query DataSets for GSE78850
Status Public on Mar 03, 2016
Title Gene expression in human prostate cancer (PCa) cell lines upon HIC1 silencing
Organism Homo sapiens
Experiment type Expression profiling by array
Summary To explore the role of HIC1 silencing in regulating PCa EMT development, Human Gene Expression Microarrays were searched for altered genes upon silencing HIC1 expression in C4-2B and DU145 cells. According to fold-change screening betweenHIC1-silenced and its respective control cells, both up-regulated and down-regulated genes were shown.
Overall design Human PCa cell lines C4-2B and DU145 were transfected with lenti-virus (shRNA targeting HIC1 and respective control). HIC1-silenced cells were respectively noted as C4-2B-shHIC1 and DU145-shHIC1. Their respective control cells were respectively noted as C4-2B-shctrl and DU145-shctrl.
Contributor(s) Hao M, Wang J
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Submission date Mar 02, 2016
Last update date Apr 23, 2018
Contact name Mingang Hao
Organization name Shanghai Jiao Tong University School of Medicine
Department Department of Biochemistry and Molecular & Cell Biology
Street address NO. 280 South Chongqing Road
City Shanghai
ZIP/Postal code 200025
Country China
Platforms (1)
GPL17077 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
Samples (4)
GSM2079472 C4-2B-shctrl
GSM2079473 C4-2B-shHIC1
GSM2079474 DU145-shctrl
BioProject PRJNA314135

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE78850_RAW.tar 49.4 Mb (http)(custom) TAR (of TXT)
GSE78850_processed_files.xlsx 11.9 Mb (ftp)(http) XLSX
Processed data included within Sample table
Processed data are available on Series record

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