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Series GSE78148 Query DataSets for GSE78148
Status Public on May 10, 2017
Title Effect of human genetic variability on gene transcription in dorsal root ganglia and association with pain phenotypes [exon-level]
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Single nucleotide polymorphisms (SNP) can affect mRNA gene expression, in a tissue-specific manner. In this work we survey association of SNP alleles with mRNA gene expression in human dorsal root ganglions (DRG) to gain insights into pathophysiology of pain phenotypes.
Overall design DNA and RNA was extracted from dorsal root ganglions of deceased human patients; the DNA used for genotyping and the RNA used for mRNA expression level measurement. Expression quantitative trait loci analyses were performed between SNP alleles and mRNA levels to evaluate strength of association between minor allele content at a given SNP and mRNA level of a given gene/exon.
Contributor(s) Parisien M, Khoury S, Chabot-Doré A, Slade GD, Smith SB, Fillingim RB, Ohrbach R, Greenspan JD, Maixner W, Belfer I, Mogil JS, Diatchenko L
Citation(s) 28564610, 31199789
Submission date Feb 22, 2016
Last update date Jul 30, 2019
Contact name Marc Parisien
Organization name McGill University
Department Dentistry
Lab Human Pain Genetics Lab
Street address 740 Dr. Penfield Avenue
City Montreal
State/province Quebec
ZIP/Postal code H3A 0G1
Country Canada
Platforms (1)
GPL17585 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [probe set (exon) version]
Samples (214)
GSM2068004 individual 6
GSM2068005 individual 7
GSM2068006 individual 8
This SubSeries is part of SuperSeries:
GSE78150 Effect of Human Genetic Variability on Gene Expression in Dorsal Root Ganglia and Association with Pain Phenotypes
BioProject PRJNA312784

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE78148_RAW.tar 4.9 Gb (http)(custom) TAR (of CEL)
GSE78148_exon-level.tsv.gz 1.5 Gb (ftp)(http) TSV
Processed data are available on Series record

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