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Series GSE77600 Query DataSets for GSE77600
Status Public on Nov 02, 2016
Title Irf3 phenotyping
Organism Mus musculus
Experiment type Expression profiling by array
Summary The interferon regulatory factors IRF3 and IRF7 are key players in the regulation of type I and III IFN genes. In this study, we analyzed the role of IRF3 and IRF7 for the host response to influenza A virus infections in Irf3-/-, Irf7-/- and Irf3-/-Irf7-/- knock-out mice.
Overall design The KO and WT mice were intranasally infected with PR8M virus or PBS for mock controls. Lungs were collected at indicated time points post infection (d3) . Total RNA from these lungs were used for microarray analysis.
Contributor(s) Schughardt K, Hatesuer B, Geffers R, Hoang H, Wilk E
Citation(s) 27811478
Submission date Feb 05, 2016
Last update date Nov 01, 2017
Contact name Robert Geffers
Phone +49 531-6181-3058
Organization name HCI - Helmholtz Centre for Infection Research
Department Dep. Molecular Bacteriology
Lab Genome Analytics
Street address Inhoffenstr. 7
City Braunschweig
ZIP/Postal code 38124
Country Germany
Platforms (1)
GPL11202 Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Probe Name version)
Samples (24)
GSM2055025 wtmd3_15
GSM2055026 wtmd3_16
GSM2055027 wtmd3_41
BioProject PRJNA310995

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE77600_RAW.tar 52.0 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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