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Series GSE7753 Query DataSets for GSE7753
Status Public on Nov 01, 2007
Title Gene Expression Profiling in Peripheral Blood in Untreated New Onset Systemic Juvenile Idiopathic Arthritis
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Systemic Juvenile Idiopathic Arthritis (sJIA) has been strongly associated with macrophage activation syndrome (MAS). To better understand the pathogenesid of sJIA and to facilitate the search for MAS biomarkers, we examine gene expression profiles in untreated new onset sJIA.
17 new onset sJIA patients were included in the study. 5 of the 17 patients showed evidence of subclinical MAS and 2 eventually developed overt MAS.
Keywords: disease versus control
 
Overall design Peripheral blood mononuclear cells (PBMCs) were separated using a Ficoll gradient from the 17 new onset sJIA patients and 30 normal control. RNA was extracted from the PBMCS and subsequently hybridized to Affymetrix microarrays
 
Contributor(s) Fall N, Barnes M, Thornton S, Luyrink L, Jennings K, Olson J, Ilowit N, Griffin T, Sherry D, Thompson S, Glass D, Colbert R, Grom A
Citation(s) 17968951
Submission date May 07, 2007
Last update date Mar 25, 2019
Contact name ndate fall
E-mail(s) ndate.fall@cchmc.org
Phone 513-636-7663
Organization name Cincinnati children's hospital medical center
Department rheumatology
Street address 3333 burnet av
City cincinnati
State/province OH
ZIP/Postal code 45229
Country USA
 
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (47)
GSM187584 01L4G: normal control
GSM187585 01L4J: normal control
GSM187586 01L4M: normal control
Relations
BioProject PRJNA99875

Download family Format
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Supplementary file Size Download File type/resource
GSE7753_RAW.tar 214.6 Mb (http)(custom) TAR (of CEL)

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