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Series GSE75816 Query DataSets for GSE75816
Status Public on Jan 14, 2016
Title Medial prefrontal cortex transcriptome changes in germ-free mice
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary We sequenced mRNA from 12 samples extracted from mouse prefrontal cortex tissue to generate the first prefrontal cortex-specific murine transcriptome for germ-free mice (GF), conventionally raised controls (CON) and germ-free mice that have been colonized with normal microbiota from postnatal day 21 (exGF).
Overall design Equal amounts of RNA from two to three animals were pooled to yield 4 samples per group (CON, GF, and exGF). Pairwise comparisons for CONvsGF, CONvsexGF, GFvsexGF were performed using DESeq2.
Contributor(s) Hoban AE, Stilling RM, Ryan F, Clarke G, Claesson M, Cryan JF, Dinan TG, Shanahan F
Citation(s) 27045844
Submission date Dec 08, 2015
Last update date May 15, 2019
Contact name Roman M Stilling
Organization name University College Cork
Department Anatomy and Neuroscience
Lab Neurogastroenterology
Street address Western Road
City Cork
ZIP/Postal code 0
Country Ireland
Platforms (1)
GPL19057 Illumina NextSeq 500 (Mus musculus)
Samples (12)
GSM1968316 CON1 medial prefrontal cortex
GSM1968317 CON2 medial prefrontal cortex
GSM1968318 CON3 medial prefrontal cortex
BioProject PRJNA305425
SRA SRP067146

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Supplementary file Size Download File type/resource
GSE75816_deseq2_output_all.xlsx 8.3 Mb (ftp)(http) XLSX
GSE75816_htseq_counts.txt.gz 530.4 Kb (ftp)(http) TXT
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