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| Status |
Public on Nov 29, 2016 |
| Title |
Parental diet affects metabolism, obesity and hypothalamic DNA methylation in Psammomys obesus |
| Organism |
Psammomys obesus |
| Experiment type |
Methylation profiling by high throughput sequencing
|
| Summary |
Using methyl CpG binding domain capture and deep sequencing (MBD-seq) we examined the hypothalamus of offspring of dams and bucks either provided ad libitum a standard rodent diet or a low fat diet before fertilisation and during gestation. The offspring were provided a standard rodent diet.
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| |
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| Overall design |
Examination of the differences in DNA methylation of offspring with different paternal diets.
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| |
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| Contributor(s) |
Khurana I, Kaspi A, Ziemann M, Connor T, Spolding B, Cooper A, Zimmet P, El-Osta A, Walder K |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Nov 30, 2015 |
| Last update date |
May 15, 2019 |
| Contact name |
Assam El-Osta |
| Organization name |
Baker Heart and Diabetes Institute
|
| Lab |
Human Epigenetics
|
| Street address |
75 Commercial Road
|
| City |
Melbourne |
| ZIP/Postal code |
3004 |
| Country |
Australia |
| |
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| Platforms (1) |
| GPL21184 |
Illumina Genome Analyzer IIx (Psammomys obesus) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA304410 |
| SRA |
SRP066784 |
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