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| Status |
Public on Feb 01, 2016 |
| Title |
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation [human cell line ChIP-seq] |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We report the distribution of H3K27Ac histone marks in multiple human melanoma cell lines with the aim of identifying super-enhancer regions and regions of interest. Also performed ChipSeq for H3K4Me1 to identify active enhancers in a representative human melanoma cell line, A375.
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| |
|
| Overall design |
Examination of H3K27Ac chromatin mark in 6 human melanoma lines. Examination of H3K4Me1 in one human melanoma cell line.
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| |
|
| Contributor(s) |
Kaufman CK, Yang S, Zon L |
| Citation(s) |
26823433 |
| |
| Submission date |
Nov 24, 2015 |
| Last update date |
May 15, 2019 |
| Contact name |
Leonard Zon |
| E-mail(s) |
zon@enders.tch.harvard.edu
|
| Organization name |
Boston Children's Hospital
|
| Department |
Oncology/Hematology
|
| Street address |
1 Blackfan Circle
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02115 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
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| Samples (14)
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| This SubSeries is part of SuperSeries: |
| GSE75356 |
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation |
|
| Relations |
| BioProject |
PRJNA304004 |
| SRA |
SRP066618 |
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