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Series GSE75176 Query DataSets for GSE75176
Status Public on Jan 04, 2016
Title Comparison of expression profiles of WT and Nrf2AY/AY mutant macrophages under electrophilic stress agent [RNA-Seq]
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Nrf2(A502Y) mutant failed to recognize cis-element required for induction of Nrf2 target genes.To examine whether Nrf2(A502Y) supports expression of a distinct gene set from that supported by Nrf2, RNA-Seq analysis was performed. We compared gene expression profiles in peritoneal macrophages from Nrf2+/+ and Nrf2AY/AY mice between basal and DEM (which is an electorophilic stress agent promoting Nrf2 induction)-treated conditions.
Overall design mRNA profiles of wild type (WT) and Nrf2AY/AY (AY) mutant macrophages under basal and DEM-treated condition were generated by deep sequencing, in triplicate.
Contributor(s) Otsuki A, Mikiko S, Katsuoka F, Tsuchida K, Suda H, Morita M, Shimizu R, Yamamoto M
Citation(s) 26677805
Submission date Nov 19, 2015
Last update date May 15, 2019
Contact name Masayuki Yamamoto
Phone 81-22-717-8084
Organization name Tohoku University Graduate School of Medicine
Department Medical Biochemistry
Street address 2-1 Seiryo-machi, Aoba-ku
City Sendai
ZIP/Postal code 980-8575
Country Japan
Platforms (1)
GPL19057 Illumina NextSeq 500 (Mus musculus)
Samples (12)
GSM1944632 WT_rep1_basal
GSM1944633 WT_rep1_DEM
GSM1944634 AY_rep1_basal
This SubSeries is part of SuperSeries:
GSE75177 Comparison of expression profiles of WT and Nrf2AY/AY mutant macrophages under electrophilic stress agent
BioProject PRJNA302713
SRA SRP066411

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE75176_AYC_vs_AYI.genes.fpkm_tracking.gz 938.8 Kb (ftp)(http) FPKM_TRACKING
GSE75176_WTC_vs_WTI.genes.fpkm_tracking.gz 945.2 Kb (ftp)(http) FPKM_TRACKING
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Raw data are available in SRA
Processed data are available on Series record

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