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Series GSE74812 Query DataSets for GSE74812
Status Public on Dec 17, 2015
Title MLL-rearranged acute lymphoblastic leukemias upregulate BCL-2 through H3K79 methylation and are highly sensitive to the BCL-2 specific antagonist ABT-199
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary We present ChIP-seq in the t(4;11) cell line SEM for different components of the MLL-AF4 complex as well as other chromatin proteins
Overall design Examination of 5 histone marks, MLL, AF4, ENL and CFP1 in t(4;11) cells
Contributor(s) Milne TA, Kerry J
Citation(s) 26711339
Submission date Nov 09, 2015
Last update date May 15, 2019
Contact name Thomas Milne
Organization name Weatherall Institute of Molecular Medicine
Department Molecular Haematology Unit
Street address John Radcliffe Hospital
City Oxford
ZIP/Postal code OX3 9DS
Country United Kingdom
Platforms (3)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
Samples (14)
GSM1934089 H3K27ac_ChIPSeq
GSM1934090 H3K4me3_ChIPSeq
GSM1934091 H3K4me1_ChIPSeq
BioProject PRJNA301600
SRA SRP065960

Download family Format
SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE74812_RAW.tar 1.5 Mb (http)(custom) TAR (of BED)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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