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Series GSE73682 Query DataSets for GSE73682
Status Public on Dec 12, 2015
Title Development of gene expression signatures for knockdown of synthetic lethal gene
Organism Homo sapiens
Experiment type Expression profiling by array
Summary We performed genome-wide expression profiling analysis to define the genes underlying the synthetic-lethal relationship between CBP and p300. We extracted 1,936 genes whose expression levels changed >2-fold upon p300-knockdown (KD) in CBP-KO cells, or upon CBP-KD in p300-KO cells, but not in either KD in wild-type cells
Overall design Gene expression profile in human lung H1299, H1299 CBP KO, H1299 p300KO cells was measured at 48 hours after transfection of siNT, siCBP or sip300. Two independent experiments were performed at each time (48 hours).
Contributor(s) Ogiwara H, Kohno T
Citation(s) 26603525
Submission date Oct 02, 2015
Last update date Nov 27, 2018
Contact name Takashi Kohno
Phone +81-3-3547-2511 (4650)
Organization name National Cancer Center Research Institute
Lab Division of Genome Biology
Street address 1-1, Tsukiji 5-chome
City Chuo-ku
State/province Tokyo
ZIP/Postal code 104-0045
Country Japan
Platforms (1)
GPL13607 Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Feature Number version)
Samples (14)
GSM1900741 H1299 siNT 48h #1
GSM1900742 H1299 sip300 48h #1
GSM1900743 H1299 siCBP 48h #1
BioProject PRJNA297663

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE73682_RAW.tar 48.9 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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