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Series GSE73342 Query DataSets for GSE73342
Status Public on Oct 31, 2016
Title Next Generation Sequencing of small non-coding RNAs in the tissue of patients with renal cell carcinoma
Organism Homo sapiens
Experiment type Non-coding RNA profiling by high throughput sequencing
Summary Non-coding RNAs play an important role in the pathogenesis of human malignancies. So far, microRNAs have been investigated in detail in clear cell renal cell carcinoma, but the knowledge about other small non-coding RNAs like snoRNA, tRNA and piRNA remains small. There is increasing evidence that these non-coding RNAs are also involved in regulation of gene expression, and we therefore performed small RNA sequencing in a cohort of 18 corresponding normal and malignant tissue samples from patients with clear cell renal cell carcinoma. We observed differential expression of microRNAs, but also some dysregulated tRNA and snoRNA in clear cell renal cell carcinoma tissue
Overall design small RNA expression profiling in clear cell renal cell carcinoma and corresponding normal renal tissues samples
Please note that each 'ccRCC' sample is followed by the corresponding normal renal tissue sample. For example, the '2014_001_002' is the corresponding normal tissue for '2014_001_001' ccRCC sample, except the last two samples 2014_001_028 and 2014_001_029 are listed in an inverse order.
Contributor(s) Ellinger J, Nientiedt M, Schmidt D, Deng M
Citation(s) 27883021
Submission date Sep 22, 2015
Last update date May 15, 2019
Contact name Jörg Ellinger
Organization name Universitätsklinikum Bonn
Department Urologie
Street address Sigmund-Freud-Straße 25
City Bonnn
State/province NRW
ZIP/Postal code 53127
Country Germany
Platforms (1)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
Samples (36)
GSM1891367 2014_001_001 [ccRCC]
GSM1891368 2014_001_002 [non pathological renal tissue]
GSM1891369 2014_001_003 [ccRCC]
BioProject PRJNA296713
SRA SRP064011

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE73342_annex_3_phase1_miRNA_read_counts.txt.gz 18.0 Kb (ftp)(http) TXT
GSE73342_annex_3_phase2_miRNA_read_counts.txt.gz 35.3 Kb (ftp)(http) TXT
GSE73342_annex_4_phase1_isomiR_read_counts.txt.gz 2.2 Kb (ftp)(http) TXT
GSE73342_annex_4_phase2_isomiR_read_counts.txt.gz 1.3 Mb (ftp)(http) TXT
GSE73342_annex_5_phase1_normalized_miRNA_expression_data.txt.gz 36.7 Kb (ftp)(http) TXT
GSE73342_annex_5_phase2_normalized_miRNA_expression_data.txt.gz 75.9 Kb (ftp)(http) TXT
GSE73342_annex_6_phase1_tRNA_read_counts.txt.gz 6.0 Kb (ftp)(http) TXT
GSE73342_annex_6_phase2_tRNA_read_counts.txt.gz 6.7 Kb (ftp)(http) TXT
GSE73342_annex_7_phase1_piRNA_read_counts.txt.gz 8.1 Kb (ftp)(http) TXT
GSE73342_annex_7_phase2_piRNA_read_counts.txt.gz 8.8 Kb (ftp)(http) TXT
GSE73342_annex_8_phase1_normalized_tRNA_expression_data.txt.gz 13.2 Kb (ftp)(http) TXT
GSE73342_annex_8_phase2_normalized_tRNA_expression_data.txt.gz 12.4 Kb (ftp)(http) TXT
GSE73342_annex_9_phase1_normalized_piRNA_expression_data.txt.gz 9.2 Kb (ftp)(http) TXT
GSE73342_annex_9_phase2_normalized_piRNA_expression_data.txt.gz 9.6 Kb (ftp)(http) TXT
GSE73342_readme.txt 2.1 Kb (ftp)(http) TXT
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Processed data are available on Series record

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