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Series GSE73078 Query DataSets for GSE73078
Status Public on Nov 01, 2015
Title Next Generation Sequencing Methylation Profiling in Skeletal Muscle from Lean and Obese Subjects [Microarray expression]
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Obesity is a metabolic disease caused by environmental, genetic, and epigenetic factors. However, the epigenetic mechanisms of obesity are incompletely understood. The aim of our study was to identify skeletal muscle DNA methylation patterns in combination with transcriptomic changes in obesity.
Overall design Muscle biopsies were obtained basally from lean (n=10) and obese (n=10) participants in combination with euglycemic hyperinsulinemic clamps to assess insulin sensitivity. We performed microarray (SurePrint G3 Human Gene Expression 8x60K v2) analysis on RNA isolated from vastus lateralis muscle biopsies. This represents the expression profiling component only.
Contributor(s) Day SE, Coletta DK, Coletta RL
Citation(s) 27437034, 28883895
Submission date Sep 16, 2015
Last update date Jul 10, 2019
Contact name Samantha Elaine Day
Organization name Arizona State University
Street address University Dr. and Mill Ave.
City Tempe
State/province AZ
ZIP/Postal code 85281
Country USA
Platforms (1)
GPL17077 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
Samples (20)
GSM1884933 T03_Lean_Normalized
GSM1884934 T04_Lean_Normalized
GSM1884935 T06_Lean_Normalized
This SubSeries is part of SuperSeries:
GSE73304 Next Generation Sequencing Methylation Profiling in Skeletal Muscle from Lean and Obese Subjects
BioProject PRJNA296052

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE73078_RAW.tar 60.3 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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