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Series GSE70871 Query DataSets for GSE70871
Status Public on Jul 14, 2015
Title Recovery and analysis of nascent RNA
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Nascent transcription profiles are shown for scaled megadomains and 100kb flanking regions before BRD4-NUT induction (0h) and at different time points (2h, 3h, 7h) following induction in 293T cells. Increase of the transcription from 0h to 7h after induction. Average level of transcriptional activity is reduced within the megadomains and their flanking regions following JQ1 treatment of TC-797 cells. Profile of nascent RNA-seq is shown for cells without JQ1 treatment, and for cells 1hr, 2.5hr and 4hr following JQ1 treatment.
Overall design Recovery and analysis of nascent RNA
Contributor(s) Kharchenko P, Wang X
Citation(s) 26220994
Submission date Jul 14, 2015
Last update date May 15, 2019
Contact name Peter Kharchenko
Organization name Harvard Medical School
Department DBMI
Lab Kharchenko
Street address 10 Shattuck St.
City Boston
State/province MA
ZIP/Postal code 02115
Country USA
Platforms (1)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (14)
GSM1820976 No_JQ1_797R1
GSM1820977 1h_JQ1_797R1
GSM1820978 2h30_JQ1_797R1
This SubSeries is part of SuperSeries:
GSE70868 The oncogenic BRD4-NUT chromatin regulator drives aberrant transcription within large topological domains
BioProject PRJNA289739
SRA SRP061033

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE70871_RAW.tar 4.8 Gb (http)(custom) TAR (of TDF)
GSE70871_RNASeq.counts.txt.gz 1.7 Mb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file
Processed data are available on Series record

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