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Status |
Public on Mar 03, 2016 |
Title |
Affymetrix Genome-Wide Human SNP Array 6.0 data for Type II Enteropathy-associated T-cell lymphoma |
Organism |
Homo sapiens |
Experiment type |
SNP genotyping by SNP array Genome variation profiling by SNP array
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Summary |
Type II Enteropathy-associated T-cell lymphoma (Type II EATL) is an aggressive intestinal T-cell lymphoma with poor prognosis and has not been molecularly profiled. Through targeted amplicon sequencing, we identified a large portion of Type II EATL samples that harbor mutations in the STAT5B, JAK3 and GNAI2 genes. Genome-wide DNA copy number profiling of Type II EATL tumors and matched normal samples was performed to determine copy-number changes in this disease.
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Overall design |
Affymetrix SNP6 arrays were performed according to the manufacturer's directions on gDNA extracted from 4 tumors and 4 matched whole blood samples.
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Contributor(s) |
Nagarajan S, Nairismägi ML, Ong CK |
Citation(s) |
26854024 |
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Submission date |
Jul 08, 2015 |
Last update date |
Nov 27, 2018 |
Contact name |
Sanjanaa Nagarajan |
E-mail(s) |
sanjanaa@duke-nus.edu.sg
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Organization name |
National Cancer Centre Singapore
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Department |
Department of Medical Sciences
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Lab |
NCCS-VARI Translational Research Laboratory
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Street address |
11 Hospital Drive
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City |
Singapore |
State/province |
Singapore |
ZIP/Postal code |
169610 |
Country |
Singapore |
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Platforms (1) |
GPL6801 |
[GenomeWideSNP_6] Affymetrix Genome-Wide Human SNP 6.0 Array |
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Samples (8)
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This SubSeries is part of SuperSeries: |
GSE70654 |
Type II Enteropathy-associated T-cell lymphoma |
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Relations |
BioProject |
PRJNA289280 |