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Series GSE70653 Query DataSets for GSE70653
Status Public on Mar 03, 2016
Title Affymetrix Genome-Wide Human SNP Array 6.0 data for Type II Enteropathy-associated T-cell lymphoma
Organism Homo sapiens
Experiment type SNP genotyping by SNP array
Genome variation profiling by SNP array
Summary Type II Enteropathy-associated T-cell lymphoma (Type II EATL) is an aggressive intestinal T-cell lymphoma with poor prognosis and has not been molecularly profiled. Through targeted amplicon sequencing, we identified a large portion of Type II EATL samples that harbor mutations in the STAT5B, JAK3 and GNAI2 genes. Genome-wide DNA copy number profiling of Type II EATL tumors and matched normal samples was performed to determine copy-number changes in this disease.
 
Overall design Affymetrix SNP6 arrays were performed according to the manufacturer's directions on gDNA extracted from 4 tumors and 4 matched whole blood samples.
 
Contributor(s) Nagarajan S, Nairismägi ML, Ong CK
Citation(s) 26854024
Submission date Jul 08, 2015
Last update date Nov 27, 2018
Contact name Sanjanaa Nagarajan
E-mail(s) sanjanaa@duke-nus.edu.sg
Organization name National Cancer Centre Singapore
Department Department of Medical Sciences
Lab NCCS-VARI Translational Research Laboratory
Street address 11 Hospital Drive
City Singapore
State/province Singapore
ZIP/Postal code 169610
Country Singapore
 
Platforms (1)
GPL6801 [GenomeWideSNP_6] Affymetrix Genome-Wide Human SNP 6.0 Array
Samples (8)
GSM1815835 N013
GSM1815836 T013
GSM1815837 N063
This SubSeries is part of SuperSeries:
GSE70654 Type II Enteropathy-associated T-cell lymphoma
Relations
BioProject PRJNA289280

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE70653_RAW.tar 232.0 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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