|
| Status |
Public on Jul 01, 2017 |
| Title |
TYRP1 knock-down in human melanoma cell line (501Mel) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Efficient TYRP1 knock-down (KD) have been performed in human melanoma cell line expressing a high level of TYRP1 mRNA and protein in order to identify the molecular pathway explaining the decrease of cell proliferation in TYRP1 KD cells.
|
| |
|
| Overall design |
Two non targeting siRNA (NT1 and NT2) and 3 siRNA targeting the ORF sequence of TYRP1 were used. Experiments have been done 3 or 4 times respectively (( NT1, NT2, TYRP1 A and TYRP1D) and (TYRP1C )). Technical duplicates have been performed to make the batch effect removal accurate.
|
| |
|
| Contributor(s) |
Mouchet N, Corre S, Gilot D, Galibert M |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Jul 06, 2015 |
| Last update date |
Nov 27, 2018 |
| Contact name |
Nicolas Mouchet |
| E-mail(s) |
nicolas.mouchet@univ-rennes1.fr
|
| Organization name |
CNRS UMR6290
|
| Department |
Institut genetique et developpement de Rennes
|
| Lab |
Regulation transcriptomique et oncogenese
|
| Street address |
2 Av du Professeur Leon Bernard
|
| City |
Rennes |
| State/province |
Bretagne |
| ZIP/Postal code |
35043 |
| Country |
France |
| |
|
| Platforms (1) |
| GPL13607 |
Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Feature Number version) |
|
| Samples (18)
|
|
| Relations |
| BioProject |
PRJNA289013 |
Less...
More...