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Series GSE70561 Query DataSets for GSE70561
Status Public on Jul 01, 2017
Title TYRP1 knock-down in human melanoma cell line (501Mel)
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Efficient TYRP1 knock-down (KD) have been performed in human melanoma cell line expressing a high level of TYRP1 mRNA and protein in order to identify the molecular pathway explaining the decrease of cell proliferation in TYRP1 KD cells.
Overall design Two non targeting siRNA (NT1 and NT2) and 3 siRNA targeting the ORF sequence of TYRP1 were used. Experiments have been done 3 or 4 times respectively (( NT1, NT2, TYRP1 A and TYRP1D) and (TYRP1C )). Technical duplicates have been performed to make the batch effect removal accurate.
Contributor(s) Mouchet N, Corre S, Gilot D, Galibert M
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Submission date Jul 06, 2015
Last update date Nov 27, 2018
Contact name Nicolas Mouchet
Organization name CNRS UMR6290
Department Institut genetique et developpement de Rennes
Lab Regulation transcriptomique et oncogenese
Street address 2 Av du Professeur Leon Bernard
City Rennes
State/province Bretagne
ZIP/Postal code 35043
Country France
Platforms (1)
GPL13607 Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Feature Number version)
Samples (18)
GSM1810397 Non targeting Si n°1 sample N°1
GSM1810398 Non targeting Si n°1 sample N°11
GSM1810399 Non targeting Si n°1 sample N°21
BioProject PRJNA289013

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE70561_RAW.tar 60.9 Mb (http)(custom) TAR (of TXT)
GSE70561_normalized_data_with_annotation.txt.gz 6.7 Mb (ftp)(http) TXT
Processed data included within Sample table
Processed data are available on Series record

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