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Status |
Public on Apr 12, 2016 |
Title |
Low and high dose TLR4 stimulation in bone-marrow derived mouse macrophages |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
The goal of this study was to compare gene expression in mouse bone marrow-derived macrophages stimulated with high or low doses of the TLR4 ligand Kdo2-Lipid A.
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Overall design |
Mouse bone marrow derived marcophages were exposed to 0.03 nM or 10 nM does of the TLR4 ligand KDO Lipid A, and RNA was harvested at 1 and 2 hours post-stimulation. Two independent experimental replicates were performed.
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Contributor(s) |
Gottschalk RA, Martins AJ, Tsang JS, Germain RN |
Citation(s) |
27237739 |
BioProject |
PRJNA288593 |
Submission date |
Jul 06, 2015 |
Last update date |
Sep 05, 2023 |
Contact name |
Andrew Martins |
E-mail(s) |
andrew.martins@yale.edu
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Organization name |
Yale School of Medicine
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Department |
Immunobiology
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Street address |
100 College Street Rm 1155
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City |
New Haven |
State/province |
Connecticut |
ZIP/Postal code |
06510 |
Country |
USA |
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Platforms (1) |
GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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Samples (10)
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Relations |
SRA |
SRP060202 |