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Series GSE69602 Query DataSets for GSE69602
Status Public on Sep 01, 2016
Title Ribosome profiling analysis of Dengue Virus
Organism Homo sapiens
Experiment type Other
Expression profiling by high throughput sequencing
Summary Dengue virus is an + strand RNA virus. We have carried our infections of human cells with Dengue and analyzed the translation, replication, and localization of the Dengue RNA. This allowed for clear definition of the life cycle of the Dengue virus inside a host cell. We also assessed the host response to Dengue virus, finding that a large fraction of the translational response is due to Interferon function.
Overall design Translational and transcriptional analysis of the cellular response to Dengue virus infection
Contributor(s) Reid DW, Campos RK, Chan KW, Nicchitta CV, Vasudevan S, Garcia-Blanco MA
Citation(s) 29321322
Submission date Jun 05, 2015
Last update date Feb 10, 2020
Contact name David Reid
Organization name Duke University
Department Biochemistry
Lab Nicchitta
Street address 436 Nanaline Duke Bldg., Box 3709 DUMC
City Durham
State/province NC
ZIP/Postal code 27710
Country USA
Platforms (1)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (116)
GSM1704503 6 h infection cytosol ribosome profiling (Rep 1)
GSM1704504 6 h infection ER ribosome profiling (Rep 1)
GSM1704505 12 h infection cytosol ribosome profiling (Rep 1)
BioProject PRJNA285961
SRA SRP059187

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE69602_DENVExpression-wholecell.xlsx 4.0 Mb (ftp)(http) XLSX
GSE69602_dengueExpression-fractionated.xlsx 2.6 Mb (ftp)(http) XLSX
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