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Series GSE69516 Query DataSets for GSE69516
Status Public on Nov 02, 2015
Title EHMT1 and EHMT2 inhibition induce fetal hemoglobin expression [ChIP-seq]
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary Using UNC0638 and genetic assays to inhibit EHMT1/2 and derepress fetal hemoglobin in adult hematopoietic cells.
Overall design ChIP-seq for 2 histone modifications and total H3 (for quantitative normalization) in biological triplicates of cord blood, adult bone marrow, and UNC0638-treated adult bone marrow.
Contributor(s) Renneville A, Van Galen P, Canver MC, McConkey M, Krill-Burger JM, Dorfman DM, Holson EB, Bernstein BE, Orkin SH, Bauer DE, Ebert BL
Citation(s) 26320100
Submission date Jun 03, 2015
Last update date May 15, 2019
Contact name Peter van Galen
Organization name Brigham and Women's Hospital / Broad Institute of MIT and Harvard
Department Hematology
Lab Van Galen Lab
Street address 4 Blackfan Circle
City Boston
State/province Massachusetts
ZIP/Postal code 02115
Country USA
Platforms (2)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
Samples (72)
GSM1702515 HiSeq_H3K9ac_hi_BM_DMSO1
GSM1702516 HiSeq_H3K9ac_hi_BM_DMSO2
GSM1702517 HiSeq_H3K9ac_hi_BM_DMSO3
This SubSeries is part of SuperSeries:
GSE71422 EHMT1 and EHMT2 inhibition induce fetal hemoglobin expression
BioProject PRJNA285772
SRA SRP059032

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE69516_H3K9ac_BM_DMSO.tdf 183.5 Mb (ftp)(http) TDF
GSE69516_H3K9ac_BM_UNC.tdf 201.9 Mb (ftp)(http) TDF
GSE69516_H3K9ac_CB_DMSO.tdf 119.5 Mb (ftp)(http) TDF
GSE69516_H3K9me2_BM_DMSO.tdf 257.4 Mb (ftp)(http) TDF
GSE69516_H3K9me2_BM_UNC.tdf 167.1 Mb (ftp)(http) TDF
GSE69516_H3K9me2_CB_DMSO.tdf 230.1 Mb (ftp)(http) TDF
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Raw data are available in SRA
Processed data are available on Series record

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